Microsoft Multiplan was an early 8-bit spreadsheet application for CP/M and MS-DOS with ports to numerous other platforms in the early 80s. Initially it competed against VisiCalc and later Lotus 1-2-3. A companion product, Microsoft Chart, provided graphing support. Multiplan was never ported to Windows, where it was replaced with Microsoft Excel. Excel also replaced Multiplan on the Macintosh platform.

Music Mentor is a comprehensive multimedia classical music tutorial, and includes a variety of sample midi files. The software includes a small built in sequencer, but also bundles Midisoft Recording Session for more advanced music editing.

MusicPrinter Plus, from Temporal Acuity Products, Inc, is a musical notation program for MS-DOS. It supports CGA, EGA, and VGA video as well as MIDI playback.

My Advanced MailList is a comprehensive mailing list manager database that supports a wide variety of label formats, embedded graphics, import/export with other databases, and printing POST-NET barcodes.

My Label Designer is a budget software title that enables users to easily and quickly make professional looking printer labels.

MyBackup was a low-end, low cost budget title that featured a simplistic, no-frills, easy to use backup utility. It can perform full backups, or backups of selected files. There were versions for DOS and Windows. Presumably based on Finot KeepTrack Plus.

MyDatabase is a small inexpensive home-oriented database program. It supports customizable entry forms, reporting, and friendly record searching.

MyDesk, from IOTA Industries Ltd, is a document search and organizer tool for scanned images. It incorporates Visioneer's PaperPort to OCR and index documents.

myHouse is a simplistic easy to use CAD program that is specifically geared towards generating home layouts. It uses 2-D editing and features the ability to render the final product in 3-D.

MyInvoices, from MySoftware Co., is a simplistic low-cost budget application that generates and stores invoices, tracks sales, fees, and time. It was marketed to service-related business individuals. The product is very narrow in scope, and for example, does not track inventory. "MyLabelmaker" and MyCheckbook"

MyLabelMaker is a low-end budget title that aids in making labels using your printer. It is the perfect way print cards for your Rolodex, or labels for your audio cassettes!

MyTreasures is a budget database program from My Software that is specifically designed for keeping track of collectibles. It features the ability to sort, print booklets, labels, reports, and Rolodex cards. Perfect for inventorying your baseball cards, coins, or VHS video collection.

Legend, from NBI, is a document processing program for Microsoft Windows 2.x. It primarily acts as a desktop publishing program, enabling users to lay out frames or embed graphics, but is can also act as a word processor. WordStar International where it became WordStar for Windows.

First released in 1993, NCSA Mosaic was the first really popular web browser. Unlike the original browser, WorldWideWeb on NeXT, Mosaic was available for the Microsoft Windows platform and added features such as inline graphics viewing. It was developed by the National Center for Supercomputing Applications at the University of Illinois at Urbana–Champaign. NCSA Mosaic was distributed freely for non commercial use, but required a license for commercial business use. It was licensed by a number of third party OEMs, including Microsoft, who used it for the basis of Microsoft Internet Explorer. In 1995, its popularly quickly gave way to Netscape Navigator.

NetManage Chameleon is a small and efficient TCP/IP networking stack and utility suite for Microsoft Windows. It includes an FTP client, Telnet client, E-mail client, and an NFS system for interoperation with Unix networks. Other GUI utilities include Bind, Finger, Ping, TFTP, FTP Server a TN3270 terminal emulator, Whois, and SNMP. Earlier versions ran on Windows 3.0 and 3.1.

Netscape Navigator/Communicator was the first commercial web browser, displacing the free NCSA Mosaic. 1.0 was first released in December 1994, and initially offered advanced features such as progressively rendering pages as they loaded. It quickly gained many other features and capabilities and became the most popular web browser in the mid 1990s. One reason for its popularity, it was licensed freely for personal and non-profit use, although companies were expected to pay for a license. It later competed with Microsoft Internet Explorer, Opera, and Safari, and eventually was open sourced in to the Mozilla browser.

Netscape Proxy Server is a networking server tool for large businesses that increases performance, security, and control for web access. It can be used to block access to certain content, such as blocking ActiveX or Java applets. Netscape Proxy Server integrates with Netscape SuiteSpot. It competed against Microsoft Proxy Server and Novell Border Manager.

NetWare LANalyzer, originally developed by Excelan Inc, is a packet analysis tool for Novell NetWare systems. It can decode packets, gather statistics, and identify physical devices on a network. The original product was a specialized piece of hardware.

Netware lite was Novell's low-end networking product. It offered peer-to-peer networking up to 25 machines, used ODI network card drivers, and offered some support for talking to full Novell Netware networks. It was sometimes bundled with DR-DOS. It was followed up by Novell Personal Netware.

NeverEnding Disk (or "NED"), from Sytron, is a personal storage manager that goes beyond just an archiver or backup tool. easily compress or migrate them to external media, and easily find and retrieve them when you need them.

Based on GeoWorks, New Deal Office was a graphical operating environment for DOS which later became Breadbox Ensemble. New Deal adds a Windows-95 like user interface with a task bar and start menu. New Deal Office targeted low-end 386 and 486 computers that were not up to the task of running Windows 95. It was also released in a "WebSuite" edition only includes the internet connectivity and web browsing tools.

NewsMaster, from Unison World, is a primitive low-cost desktop publishing program aimed at home users and low end PCs. It supports both dot-matrix and laser printers. Separate clipart libraries were also available, and it could make use of PrintMaster clipart.

HP NewWave is an alternate shell for Microsoft Windows that gives it an icon-object desktop. It attempts to hide the file system from the user, instead presenting them with "objects" that may have many more properties and longer descriptions. It supports a feature called "Hot connects" that automatically updates data across different files.

NewWord is a clone of WordStar created by former MicroPro employees. It filled a gap for WordStar users as WordStar 3.3 went unupdated, and eventually became the basis for WordStar 4.0.

Originally written by Symantec and sold as Symantec Antivrus for Macintosh, it became part of the "Norton" branded products sold by Symantec after they acquired Peter Norton Computing. Norton Anti-Virus became a popular product on DOS, Windows, and Macintosh (SAM was renamed to NAV in 1998) and battled the then-new threat of malicious software. In 2015, Symantec unified their security product lineup under the single "Norton Security" product. It was also bundled with Norton SystemWorks.