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Digital Research C is a compiler developed for use with Digital Research's CP/M systems. It was also ported to DOS.
PL/I is a programming language oriented towards scientific and business programming. Digital Research provided implementations for their CP/M operating system as well as MS-DOS.
Smalltalk/V was the first widely available version of Smalltalk. It was developed by Digitalk in 1986 for DOS, Macintosh, and later Windows.